Death-inducing proteins key to complications of bone marrow transplantation

Treatment for a number of cancers and other medical conditions is transplantation with bone marrow from a genetically nonidentical individual. Researchers have now identified several molecules involved in a process that contributes to two medical complications that occur in patients following allo-BMT, susceptibility to infections and recurrence of cancers. Some of these molecules might prove good drug targets to improve outcome following allo-BMT.